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Whether you can take Tadalafil at the same time as your other medications will depend on which medications you are taking.

You are required to complete a short medical consultation questionnaire that asks for any medications that you are prescribed from your GP and will indicate the medications that can’t be taken alongside Tadalafil.

There are several medicines which should not be taken concurrently with Tadalafil. Medicines which can have potentially serious interactions with Tadalafil include :-

• Any alpha-blocker medicines e.g. doxazosin (Cardura), alfuzosin (Xatral), tamsulosin, terazosin, or Flomax, that you can buy in the pharmacy. (These medicines may be used to treat prostate problems or high blood pressure).

• Isosorbide mononitrate, isosorbide dinitrate, or use a GTN spray or tablets

for chest pain or use Rectogesic ointment?

• Nicorandil (Ikorel), used to treat angina

• Cimetidine, used to treat stomach or duodenal (peptic) ulcers

• Theophylline, used to treat asthma

• Antibiotics:- Clarithromycin, Erythromycin and Telithromycin

• Anti-fungals such as itraconazole and ketoconazole

• Seizure medication:- carbamazepine, oxcarbazepine, phenobarbital, phenytoin and primidone

• Heart or blood pressure medication:- disopyramide, amiodarone, quinidine and procainamide

• Anti-viral medication:- telaprevir, atazanavir, retonavir, indinavir, saquinavir and cobicistat

• Recreational drugs:- amyl nitrate (poppers)

If you are taking any prescribed medication from your GP then you can simply write those in the “Is there any other medical information that you think our doctor should know?” section on the medical questionnaire. Then, our doctor will know whether the Tadalafil is safe for you to take.

Read available consultation questionnaire

What are Tadalafil (Tadalafil CR) tablets?

Tadalafil tablets are a combination medication containing Tadalafil (Cialis) and Amyl Nitrate to help treat erectile dysfunction. These tablets are available to buy online from a pharmacy of your choice.

To treat erectile dysfunction you are required to have a consultation with a GP or a hospital. The GP or hospital can then ask you about your medical history to determine if Tadalafil is appropriate for you. This group of doctors will be able to advise you whether Tadalafil is the right medication for you and your sexual problems.

How do I take Tadalafil?

You can take Tadalafil tablets either as a single daily dose or as a combination with a at least one other medicines of the same medicines- such as :-

  • Tadalafil tablets, also known as Cialis tablets.

You should start to feel better within 30 minutes to 5 hours after taking Tadalafil tablets. The effects of Tadalafil can last for up to 5 hours.

Your GP may recommend that you take Tadalafil at the same time each day until you have an answer toicipated at least 1 of the following questions :-

  • At the start of taking the tablet, how long it takes you to start feeling better and how long it varies from person to person?- how well does Tadalafil taken together with any of the other medications in the same medicine group (e.g. nitrates, shouldRA etc)?- how soon does Tadalafil taken with any of the other medications in the same medicine group (e.g. nitrates, NDC etc)?- how well does Tadalafil dosage do with any of the other medications in the same medicine group (e.g.

Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
Ricanourced University of women take complete care. https://www.prax.org/bot/mens/harms/bayer/harms/harms-harms-sildenafil.html#BODYPLUCKER& ALTHUGIUMSouth Korea's National Healthcare Centre (NHC) (c) 2018

Healthcare Economic Status:

Healthcare Economic Status: 'SA' (over the phone)

SA Health Care Economic Status: 'SA' Not Available

Can I Buy Top Drug-Food Interactions For?

Yes, you can buy these drugs-food interactions and medications-food Interactions with your choice of your healthcare provider.

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Cialis has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.

Common side effects reported from Cialis use include:

  • Headache
  • Indigestion
  • Heartburn
  • Upset stomach
  • Gas
  • Nausea
  • Flushing

More severe side effects include:

  • Painful erections or erections that last longer than 4 hours
  • Sudden loss of vision
  • Sudden loss of hearing
  • Ringing in the ears
  • Chest pain
  • Shortness of breath
  • Painful urination
  • Increased urination frequency
  • Fainting
  • Dizziness
  • Skin rash
  • Hives
  • Facial swelling

If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.

As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Cialis. Cialis can interact with bodily substances, causing potentially serious adverse reactions.

Specifically, you should inform your health care provider of any alpha-blocker, antifungal, HIV protease inhibitor, or high blood pressure medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.

In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.

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As with most medications, Cialis can reduce the effectiveness of the medication. However, it’s important to consult your doctor before taking Cialis, especially if you have heart conditions, heart problems, low blood pressure, or other significant health conditions.

Tell them if you are related to Cialis or if you have ever had an allergic reaction to Cialis or any other drugs of the day.

In addition, let your doctor know if you are pregnant or plan on becoming pregnant. Cialis can reduce the effectiveness of the medication and increase the risk of side effects.

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It’s important to consult your doctor before taking, planning on, and/or using Cialis. Cialis can also cause an allergic reaction, which may indicate a rare reaction, such as a rash or itching.

If you experience any of these, inform your health care provider of any medical condition, including heart problems, low blood pressure, or a history of priapism, which is a painful, prolonged, or occasionally stops the blood vessels in your penis.

In addition, let your doctor know if you are breastfeeding. Cialis can increase the risk of side effects in infants under 12 years of age.

In addition, let your doctor know if you are having liver problems or are pregnant or plan to become pregnant. Cialis can increase the risk of side effects in nursing infants.

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It’s important to consult your doctor before taking, planning on, and/or using Cialis, especially if you experience any of the side effects